Japan's yen weakened to a near 38-year low; Asia-Pacific markets set to open lower

• The Japanese yen weakened to a near 38-year low late Wednesday, dropping to 160.82 against the U.S. dollar, according to FactSet data.
• Investors in Asia will also look toward China's May industrial profit numbers and Japan's retail sales data on Thursday.

Asia-Pacific markets were set to open lower on Thursday, as the Japanese yen weakened to a near 38-year low late Wednesday, hitting160.82 against the U.S. dollar, according to FactSet data.

The yen last breached the 160 level against the dollar two months ago, prompting the Japanese government to prop it up in the country's first currency intervention since 2022.

Investors in Asia will also look toward China's May industrial profit numbers and Japan's retail sales data which will be released on Thursday.

Futures for Australia's S&P/ASX 200 stood at 7,689, lower than their last close of 7,783.

Japan's Nikkei 225 futures pointed to a stronger open for the market, with the futures contract in Chicago at 39,405 and its counterpart in Osaka at 39,420 compared to the previous close of 39,667.07.

Hong Kong Hang Seng index futures were at 17,947, lower than the HSI's last close of 18,089.93.

Overnight in the U.S., the Dow Jones Industrial Average added 0.04%, while the S&P 500 rose 0.16% and the Nasdaq Composite gained 0.49%. The Nasdaq's climb was led by Amazon shares, which recorded a 3.9% jump.

The stock hit an all-time high and reached $2 trillion in market value for the first time on Wednesday, joining Nvidia, Apple, Alphabet and Microsoft.

—CNBC's Hakyung Kim and Brian Evans contributed to this report.