Rutgers students make significant finding in Alzheimer's disease

rutgers students make significant finding in alzheimer's disease

Brain scan of a patient with a deep brain stimulation (DBS) therapy device.

A group of Rutgers students made a significant scientific finding regarding Alzheimer’s disease, according to the university.

The group of undergraduate students found that a drug called yoda1 may help cure Alzheimer’s, by helping the brain drain out waste that causes dementia.

Alzheimer’s is a type of dementia associated with the brain’s inability to clean itself by draining out neurotoxins. The brain’s lymphatic system is what rids the brain of such neurotoxins, and it is the main focus in this Rutgers research.

“The brain’s lymphatic system is one of the hottest research areas in all of medicine right now because it has only been re-discovered in the past 10 years, and it’s clearly vital to healthy brain function and, very likely, developing dementias like Alzheimer’s,” said Max Tischfield, a resident scientist at Rutgers Medical School involved in the research, in a statement.

The experiment conducted by Rutgers students consisted of supplying yoda1 to mice familial with Alzheimer’s that had faulty brains unable to filter neurotoxins out. After administering the drug, the mice showed significant improvement on their brain’s lymphatic system to drain out neurotoxins.

More: Want to live healthier longer? Scientists aim to improve life quality over quantity

Yoda1 has yet to undergo human trials. Currently, the Rutgers research student group is studying the mechanism yoda1 uses to improve brain lymphatic functions, according to a news release.

“There’s particular excitement because research to date has found that it (the brain’s lymphatic system) degenerates dramatically with age, so any breakthrough that maintains its function might help prevent age-related cognitive decline,” said Tischfield, who also teaches cell biology and neuroscience at Rutgers.

This article originally appeared on Asbury Park Press: Rutgers students make significant finding in Alzheimer’s disease

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