Tan earned a BA in chemistry from the University of Natural Sciences under the Vietnam National University-HCM City in 2009. The same year, he applied for a training program of metal-organic framework (MOF) material run by his university and University of California Los Angeles. He participated in the program in 2010. Research on metal-organic framework material in Vietnam was very new in 2010, which combined both organic chemistry and material science applied to solving problems of energy, medicine and environment. It was believed to be a research direction very close to the direction of global research at that time and applications from metal-organic framework material were hoped to bring useful things to life, Tan said when he explained why he had researched new materials and was recruited for the doctoral training program in molecular and nano-architecture under the cooperation program between VNU-HCM and UCLA.
For the first time, he was published in an international scientific publication of metal-organic framework material in 2015 after tireless efforts for five years, and completed the doctoral program after 7 years of research.
After graduating, with outstanding professional ability, Hoang Tan was selected to go to Japan to do post-doctoral research with Professor Fuyuhiko Tamanoi (UCLA University and Kyoto University) to jointly research and develop the generation of new nano-materials for biomedical application.
Dr. Doan Le Hoang Tan said that there are many anticancer drugs in nature, but these drugs do not dissolve in water, so they cannot reach cancer cells. Therefore, his and his colleagues' research aims to design nanomaterials that are biocompatible, biodegradable, and capable of bringing targeted drugs into cancer cells for treatment.
Hoang Tan began researching and developing biodegradable nano-silica material to carry and transmit anticancer drugs.
He said, in cancer treatment, when injecting anticancer drugs into the body, apart from cancer cells, the drugs could also affect normal cells, causing the cells to weaken or die, leading to side effects and adversely affecting the patient's health.
Therefore, research on a method to correctly transmit anticancer drugs to cancer cells was always important in cancer treatment.
To carry out this work, Dr. Hoang Tan's group used a chicken egg model to study. This is a new research direction on cancer treatment that is very quickly developing and attracts attention in Japan and around the world because of its high efficiency. Dr. Doan Le Hoang Tan said the research results have helped him a lot in teaching at VNU-HCM.
According to Assoc. Prof. Dr. Phan Bach Thang, INOMAR Director, Dr. Doan Le Hoang Tan always shows his talent and responsibility in both his roles as researcher and manager. Recently, Tan successfully studied material carrying and transmitting anticancer drugs.
Dr. Tan said in the future, he would continue his two directions of research in organic chemistry and in MOF application of MOF in biomedical./.Compiled by BTA