Tester historisk kreftsprøyte: – Kan bli livreddende

Tester historisk kreftsprøyte: – Kan bli livreddende

En historisk studie er i gang i England. For første gang har britiske pasienter fått teste tidenes første kreftsprøyte mot føflekkreft.

Injeksjonen er skreddersydd for hver enkelt pasient og bygger på mRNA-teknologi. Eksperter i både England og Norge hyller nå forsøkene og kaller det en «gamechanger».

– Håpet er at det skal bli en kreftbehandling med langt færre bivirkninger enn dagens behandlinger. Noe som er kjempespennende, forteller Generalsekretær i Kreftforeningen, Ingrid Stenstadvold Ross til Nettavisen.

– Fremtidens kreftbehandling

– Det er noe av det mest spennende vi har sett på veldig lenge. Det er et veldig følsomt verktøy, forteller Heather Shaw, som leder studien i England, til Sky News.

Studien gjennomføres ved University College London Hospitals NHS Foundation Trust.

tester historisk kreftsprøyte: – kan bli livreddende

OPTIMIST: Ingrid Stenstadvold Ross, generalsekretær i Kreftforeningen. Foto: Jorunn Valle Nilsen

Sprøyten er i første omgang rettet mot føflekkreft og skal hindre at pasienter får tilbakeslag fra sykdommen. Føflekkreft er den vanligste formen for hudkreft i verden.

Injeksjonen har også potensial til å stoppe blære-, lunge- og nyrekreft, anslår flere eksperter.

Studien går nå inn i en fase 3, der det blir testet på flere britiske pasienter, etter at fase 2 av studien viste at de som ble gitt vaksinen sammen med immunterapi, hadde nesten 50 prosent mindre sjanse for å få tilbakefall eller død etter tre år. Det skriver The Guardian.

tester historisk kreftsprøyte: – kan bli livreddende

LEDER: Dr. Heather Shaw leder studien i England. Foto: Pa (NTB)

Sprøyten er designet for å trigge immunsystemet til pasienten, slik at det kan kjempe mot en pasients spesifikke type kreft eller svulst. Noe som skiller den stort fra dagens behandlinger.

– Dette kan bli livreddende behandling for mange kreftpasienter. Håpet er at dette blir fremtidens kreftbehandling, og at den vil være mer treffsikker og med færre bivirkninger enn det vi har i dag, sier Ross.

Forskes på i Norge

Generalsekretæren sier stadig flere studier i verden forsker på lignende sprøyter mot ulike krefttyper.

Blant annet har det norske bioteknologiselskapet Nykode Therapeutics begynt en fase 2-studie for en lignende sprøyte, men for de med livmorhalskreft. Studien vil finne sted i USA, skriver Finansavisen.

tester historisk kreftsprøyte: – kan bli livreddende

MRNA: Sprøyten er personifisert og bygger på MRNA-teknologi. Foto: Pa (NTB)

– Dagen i dag markerer et viktig steg fremover i vår innsats for å forbedre kreftbehandling med oppstart av fase 2-studien av VB10.16. Samarbeidet mellom GOG og Nykode introduserer en ny og lovende fremgangsmåte for å møte et betydelig udekket medisinsk behov, sier Bradley Monk, direktør i GOG, i en pressemelding.

– Vi er optimistiske rundt hvordan vi potensielt kan endre landskapet for kreftbehandling og bidra til forbedringer som kan gjøre en meningsfull forskjell i pasientenes liv, sier Monk.

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