Shorter Course of Post-Op Radiation May Work Well for Prostate Cancer Patients

Asia's Tech News Daily

WEDNESDAY, Oct. 27, 2021 (HealthDay News) — After prostate cancer surgery, men can safely undergo fewer radiation treatments at higher doses, a new clinical trial shows.

Shorter Course of Post-Op Radiation May Work Well for Prostate Cancer Patients
© Provided by HealthDay

Researchers found that the shorter regimen — given over five weeks, instead of seven — did not raise patients’ odds of lasting side effects.

Safety has been a “major concern” because when patients have fewer radiation treatments, the daily dose needs to be higher, explained Dr. Neha Vapiwala, a radiation oncologist who was not involved in the study.

But the new findings offer “level-one evidence” that a shorter course can be delivered safely, said Vapiwala, a professor at the University of Pennsylvania, in Philadelphia.

Prostate cancer is a highly treatable disease. In the United States, the 10-year survival rate stands at 98%, according to the American Society for Radiation Oncology. That means the impact of treatment choices on men’s quality of life is particularly critical.

A shorter course of radiation is obviously appealing for its convenience. The new study was designed to find out whether fewer treatments would come at the expense of lasting side effects.

According to lead researcher Dr. Mark Buyyounouski, “Preserving quality of life was a major priority when testing the shorter treatment course. It is important for patients to know that accepting a more convenient treatment doesn’t mean they have to compromise on quality of life.”

The trial involved 296 men who’d undergone surgery for prostate cancer and needed follow-up radiation. Around half were randomly assigned to receive standard doses over seven weeks, while the rest were given higher doses over five weeks.

By the end of treatment, men on the higher-dose regimen were reporting more gastrointestinal symptoms, like cramps, diarrhea and nausea. But those problems resolved in both groups of patients, and were gone when the men were assessed six months later.

Radiation for prostate cancer can also sometimes cause urinary problems, like leakage or burning during urination. But on average, neither study group showed an increase in those symptoms, in the short term or over the two years after treatment.

“Short-term side effects of radiation therapy are well-established, and patients understand that,” said Buyyounouski, a professor of radiation oncology at Stanford University School of Medicine, in California.

“What patients ultimately want to know is whether the side effects will go away, and that’s what we saw in our study,” he said in a society news release.

Buyyounouski presented the findings Monday at the annual meeting of the American Society for Radiation Oncology, held in Chicago. Research reported at meetings should be considered preliminary until published in a peer-reviewed journal.

Short courses of radiation are not new in prostate cancer. They have been an option for men who forgo surgery and opt to have radiation therapy alone.

However, shorter courses have not been routinely offered to patients who’ve had surgery, Vapiwala said. Most doctors, she added, have been waiting for clinical trial evidence first.

Shorter radiation regimens are not only more convenient for patients, Buyyounouski said in a meeting news release: They can also lessen their travel expenses and co-pays, and limit time away from work.

There are also benefits for the health care system, he noted, as insurers pay for fewer treatments, and radiation facilities can take more patients.

Vapiwala said the trial is “incredibly important” in showing that the shorter, higher-dose approach can be done safely.

“While there may be increased patient-reported side effects,” she said, “these toxicities generally resolve with time and were not markedly worse with the shorter course compared to the standard one.”

More information

The American Cancer Society has more on treating prostate cancer.

SOURCES: Neha Vapiwala, MD, professor, radiation oncology, University of Pennsylvania Perelman School of Medicine, Philadelphia; Oct. 25, 2021 presentation, American Society for Radiation Oncology annual meeting, Chicago

Internet Explorer Channel Network
Asia's Tech News Daily
News Related

OTHER NEWS

Teddy Bridgewater: Dan Campbell's speeches make you want 'to punch a guy in the face for no reason'

It’s not just kneecaps opponents have to worry about when playing Dan Campbell-coached teams. One of Campbell’s former players with the New Orleans Saints said Campbell, now the Detroit Lions ... Read more »

Hong Kong tycoon, two others convicted over Tiananmen vigil

The Associated PressFILE – In this Feb. 9, 2021, file photo, democracy advocate Jimmy Lai leaves the Hong Kong’s Court of Final Appeal in Hong Kong. Hong Kong tycoon and ... Read more »

Activists oppose Bigler Stouffer execution set for Thursday morning

Most people who commit murder in the United States will not be put to death. That's a fact that Abraham Bonowitz, an activist with Death Penalty Action, is thankful for, ... Read more »

Ahmaud Arbery case shines light on continued miscarriages of justice in legal community

On June 21, 1964, my brother Andrew Goodman, along with two other civil rights workers James Chaney and Michael Schwerner, was kidnapped and murdered by members of the Ku Klux ... Read more »

Key moments in the police shooting of Daunte Wright

The Associated PressFILE – In this April 22, 2021, file photo, a mourner holds a program for the funeral services of Daunte Wright at Shiloh Temple International Ministries in Minneapolis. ... Read more »

USA Gymnastics looking for new head of women's team after high-performance director departs

There will be someone new leading the U.S. women’s gymnastics team at the Paris Olympics. Tom Forster, the high-performance director, is stepping down at the end of the year. The ... Read more »

Smith, Asberry power No. 5 Baylor past Alcorn State 94-40

WACO, Texas (AP) — NaLyssa Smith had her ninth consecutive double-double, Ja’Mee Asberry matched her career best with six 3-pointers and scored a season-high 20 points as No. 5 Baylor ... Read more »

Family, friends gather to remember Largo woman found dead in New Port Richey

1 / 4Family, friends gather to remember Largo woman found dead in New Port Richey Outside a home located just 50 yards from where the missing woman’s body was found, ... Read more »

Remains found in car belonging to US student who disappeared 45 years ago

The car, pulled out of a creek on Tuesday, contained what are thought to be human bones, along with identification and credit cards belonging to the car's owner, Kyle Clinkscales. Read more »

Sam Kerr levels pitch invader during UEFA Women's Champions League match between Chelsea and Juventus

With stadium security nowhere to be found when a fan ran onto the field during a UEFA Women’s Champions League game between Chelsea and Juventus, Chelsea player Sam Kerr took ... Read more »

Mikes scores 28, TCU defeats Utah 76-62

FORT WORTH, Texas (AP) — Mike Miles matched his career high with 28 points and TCU defeated Utah 76-62 on Wednesday night. Emanuel Miller and JaKobe Coles added 10 points ... Read more »

Blackwood, Devils send Flyers to 10th straight loss, 3-0

NEWARK, N.J. (AP) — Mackenzie Blackwood made 25 saves and the New Jersey Devils snapped a four-game skid and sent the reeling Philadelphia Flyers to their 10th straight loss, 3-0 ... Read more »

Cuba detects first Omicron case - state media ACN

Spread of the coronavirus disease (COVID-19) in Cuba HAVANA (Reuters) -Cuba has detected its first case of the Omicron coronavirus variant in a person who had traveled from Mozambique, Cuban ... Read more »

Officers investigate body found in burned camper

Dec. 8—Flathead County authorities are investigating the death of a person found inside a burned camper trailer on Blacktail Mountain. According to Sheriff Brian Heino, a call came in at ... Read more »

Harrison lifts ULM past NAIA Louisiana College 89-68

MONROE, La. (AP) — Russell Harrison had 24 points as ULM routed Louisiana College 89-68 on Wednesday night. Andre Jones had 18 points and eight rebounds for ULM (5-4), which ... Read more »

Covid 19 coronavirus: Mandatory vaccine passports introduced at Victoria University from 2022

Vaccine passports will now be mandatory for everyone at Victoria University of Wellington in 2022, with around 1 per cent of staff and students indicating they will not be vaccinated. ... Read more »

Linsley making big impact for Chargers on and off field

COSTA MESA, Calif. (AP) — Even though Corey Linsley has had a hectic first season with the Los Angeles Chargers, it hasn’t affected his ability to make an impact on ... Read more »

Avs beat New York 7-3; Trouba delivers another hard check

NEW YORK (AP) — Logan O’Connor scored twice in a 22-second span in a five-goal second period, and the Colorado Avalanche beat the Rangers 7-3 on Wednesday night, ending New ... Read more »

Japan's COVID-19 cases defy Asia rebound, yet fears remain for winter wave

Pedestrians wearing protective masks, amid the coronavirus disease (COVID-19) outbreak, make their way at the Ameyoko shopping district in Tokyo By Rocky Swift TOKYO (Reuters) – Japan's COVID-19 infections are ... Read more »

Sherman, West Virginia outlast No. 15 UConn 56-53

MORGANTOWN, W.Va. (AP) — Taz Sherman scored 23 points and West Virginia held on for a 56-53 victory over No. 15 UConn on Wednesday night. The Mountaineers (8-1) were terrible ... Read more »

Owusu leads No. 8 Maryland women past Purdue 86-71

COLLEGE PARK, Md. (AP) — Ashley Owusu scored eight of her 20 points in the fourth quarter to push No. 8 Maryland to an 86-71 victory over Purdue on Wednesday ... Read more »

Cardet lifts Samford over Alabama State 74-64

MONTGOMERY, Ala. (AP) — Wesley Cardet Jr. had 27 points and 11 rebounds as Samford beat Alabama State 74-64 on Wednesday night. Jaden Campbell had 14 points and 11 rebounds ... Read more »

Saint Bonaventure tops Loyola (Md) 84-71

OLEAN, N.Y. (AP) — Jalen Adaway and Jaren Holmes scored 22 points apiece as St. Bonaventure beat Loyola (Md.) 84-71 on Wednesday night. Dominick Welch had 16 points and seven ... Read more »

Marking one year in office, L.A. D.A. Gascón touts accomplishments, spars with critics on crime

Los Angeles County Dist. Atty. George Gascón touted his office’s accomplishments in his first year in office during a Wednesday news conference. (Irfan Khan / Los Angeles Times) On his ... Read more »

Embiid scores 32, 76ers hold off Hornets again 110-106

CHARLOTTE, N.C. (AP) — Joel Embiid had 32 points, Seth Curry added 23 points and eight assists, and the Philadelphia 76ers beat the Charlotte Hornets for the second time in ... Read more »

Black carries Missouri State over UALR 81-55

LITTLE ROCK, Ark. (AP) — Ja’Monta Black scored 25 points as Missouri State routed Arkansas-Little Rock 81-55 on Wednesday night. Isiaih Mosley added 21 points and Jaylen Minnett had 17 ... Read more »

First migrants returned under 'Remain in Mexico' policy

FILE – Asylum seekers wait for news of policy changes at the border on Feb. 19, 2021, in Tijuana, Mexico. The Biden administration is set to reinstate a Trump-era policy ... Read more »

New Zealand plans lifetime ban on cigarette sales to stamp out smoking

(Reuters) – The New Zealand government plans to ban young people from ever buying cigarettes in their lifetime in one of the world's toughest crackdowns on the tobacco industry, arguing ... Read more »

Couple accused in Navy submarine spy case wanted to leave US because of Trump, lawyer says

Lawyers for a Maryland woman charged along with her husband in a scheme to sell Navy submarine secrets to a foreign government denied Wednesday that she had contemplated fleeing the ... Read more »

New mommy Shriya Saran reveals how she shed post pregnancy weight in no time by following THESE two methods

© Provided by BollywoodLife.com It was in October that actress Shriya Saran revealed that she has embraced motherhood. She surprised all her fans as she announced it on social media ... Read more »

Yes, eggs can help you lose weight — here are the most nutritious ways to eat them

© etienne voss/Getty Images Yes, eggs can help you lose weight — here are the most nutritious ways to eat them Eggs can help you lose weight because of their ... Read more »

Garland scores 24 points, Cavaliers beat Bulls 115-92

CLEVELAND (AP) — Darius Garland scored 24 points and rookie power forward Evan Mobley had 16 points and nine rebounds, sending the Cleveland Cavaliers to a 115-92 win over the ... Read more »

Waitrose sales of vol au vent soar by 25%

© Provided by Daily Mail MailOnline logo Like a lot of 1970s cuisine, the vol au vent had rather fallen out of favour in recent years. However, the staple of ... Read more »

Mack scores 28 to lead Wofford over Gardner-Webb 78-70

BOILING SPRINGS, N.C. (AP) — B.J. Mack had a career-high 28 points plus 13 rebounds as Wofford defeated Gardner-Webb 78-70 on Wednesday night. Max Klesmit had 16 points for Wofford ... Read more »

Blackwood blanks reeling Flyers as Devils end 4-game skid

NEWARK, N.J. (AP) — Mackenzie Blackwood made 25 saves and the New Jersey Devils snapped a four-game skid and sent the reeling Philadelphia Flyers to their 10th straight loss, 3-0 ... Read more »

Sherman scores 23, West Virginia beats No. 15 UConn 56-53

MORGANTOWN, W.Va. (AP) — Taz Sherman scored 23 points and West Virginia held on for a 56-53 victory over No. 15 UConn on Wednesday night. The Mountaineers (8-1) were terrible ... Read more »

Pantone's 2022 color of the year symbolizes how COVID-19 has transformed the world

2021 has been a transformative year: Coming out of COVID-19 quarantine, much of the world has reexamined daily life practices and invented new ways to interact, conduct business and live ... Read more »

Wisconsin overcomes 22-point deficit to defeat Indiana in Big Ten men's basketball game

MADISON, Wis. — The reality of Big Ten play smacked Greg Gard’s Wisconsin’s players in the jaw Wednesday night at the Kohl Center. For 20 minutes. As they had during ... Read more »

UO hostage situation suspect, on supervised release since Monday, next court date in January

University of Oregon Police Chief Matthew Carmichael talks to the media about the armed suspect who allegedly held students captive in a dorm room. The man accused of holding two ... Read more »

Waukesha parade suspect Darrell Brooks hit with new charges in previous incident involving his girlfriend

The man accused of plowing into a crowd and killing six people last month at the Waukesha Christmas Parade has been hit with new charges alleging that he intimidated his ... Read more »
On free-english-test.com you will find lots of free English exam practice materials to help you improve your English skills: grammar, listening, reading, writing, ielts, toeic