Oklahoma City had few answers for Wood, who went 13 for 19 from the field, including 4 of 6 from the 3-point line. Fourth in Most Improved Player voting last season, he also blocked four shots and had a steal.
The Rockets looked much better than they did in their 124-106 season-opening loss in Minnesota on Wednesday night.
Second-overall draft pick Jalen Green had nine points in his home debut. Alperen Sengun, the 16th overall pick, had six points and five rebounds off the bench. Including Green, Sengun, and fellow first-round picks Josh Christopher and Usman Garuba, the Rockets played four 19-year-olds.
Shai Gilgeous-Alexander and Mike Muscala led Oklahoma City with 13 points apiece, and Kenrich Williams scored 12 points off the bench. Oklahoma City shot just 37% from the field and made 9 of 16 free throws.
Houston dominated Oklahoma City in the paint, outscoring the Thunder 58-34 and winning the rebounding battle 53-40.
The Rockets jumped to a double-digit lead early and led 33-21 at the end of the first quarter and led 69-47 at halftime.
The Thunder fell to 0-2 after dropping their opener to Utah on Wednesday night.
Thunder: Oklahoma City allowed 21 second-chance points to the Rockets and scored only 11 second-chance points. … Luguentz Dort had eight points on 3-of-9 shooting in 27 minutes.
Rockets: Danuel House Jr. made his season debut after missing the opener for an unspecified personal reason. House had two points and three rebounds in 11 minutes off the bench.
Thunder: Host Philadelphia on Sunday.
Rockets: Host Boston on Sunday.Internet Explorer Channel Network