Pfizer: Trial Shows COVID-19 Booster Shot ‘Restored Vaccine Protection'

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Pfizer on Thursday reported that the first efficacy results from a randomized, controlled COVID-19 booster shot trial found that a third dose of its shot restored protection to levels seen after the second dose.

© (Lynne Sladky/AP) A healthcare worker receives a Pfizer COVID-19 booster shot at Jackson Memorial Hospital Tuesday, Oct. 5, 2021, in Miami. This follows a recent recommendation by the Food and Drug Administration and Centers for Disease Control and Prevention advising people who are 65 and older, and workers whose jobs put them at high risk of exposure – including those in healthcare – to receive a booster shot six months after their second shot. (AP Photo/Lynne Sladky)

The company reported that those who got a third Pfizer dose after completing a two-shot series saw “restored vaccine protection against COVID-19 to the high levels achieved after the second dose, showing a relative vaccine efficacy of 95.6% when compared to those who did not receive a booster.”

“Based on these findings we believe that, in addition to broad global access to vaccines for everyone, booster vaccinations could play an important role in sustaining pandemic containment and a return to normalcy,” Ugur Sahin, CEO of BioNTech, which partnered with Pfizer on the vaccine, said in a statement.

The trial, which included more than 10,000 participants 16 years old and older, did not find any safety issues with the booster shot. Pfizer said it will submit the trial results to be peer-reviewed and published in a journal. It also said it will share the data with the Food and Drug Administration and other agencies “as soon as possible.”

The FDA granted emergency use authorization to Pfizer for a third shot of its vaccine in certain populations last month. President Joe Biden publicly got his Pfizer booster dose. The agency on Wednesday authorized use of Moderna and Johnson & Johnson booster shots, as well as the “mix and match” strategy.

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