FDA to Allow 'Mix and Match' COVID Boosters, But Which One Should You Get?

Asia's Tech News Daily

© Provided by Health Alex Sandoval

If you’ve been fully vaccinated against COVID-19, is it OK to switch to a different manufacturer’s product for your booster dose? If you ask the US Food & Drug Administration (FDA), the answer is yes. Under a newly announced “mix-and-match” strategy, people who got a Pfizer, Moderna, or Johnson & Johnson (J&J)/Janssen COVID vaccine may switch to another brand’s booster.

© Alex Sandoval What to know about switching brands when it’s time for your booster.

After reviewing available data, the FDA concluded that “the known and potential benefits” of using a single mix-and-match, or “heterologous,” booster dose outweigh “the known and potential risks’ in people eligible for boosters.

The US Centers for Disease Control and Prevention (CDC) has yet to revise its guidance. The CDC’s Advisory Council on Immunization Practices is slated to hear a presentation on mix-and-match data during its October 21 meeting.

Download our mobile app

So if you’re looking for a booster dose, what should you do? Here’s the latest on the FDA’s mix-and-match approach.

RELATED: FDA Panel Recommends J&J Booster Shot—Here’s What Happens Next

Why mix and match COVID vaccines?

Mixing vaccines has a couple of advantages. From a practical standpoint, the ability to switch from one manufacturer’s vaccine to another gives Americans more flexibility when they go to the doctor’s office or a pharmacy for a booster shot: No Pfizer in stock? Get the Moderna. Or so the thinking goes.

“This is going to give them some of that flexibility to go ahead and get boosted with what is convenient, whether that’s what their physician might have in their office or what the local health department or vaccine clinics may have,” Eric Adkins, MD, a professor of emergency medicine and critical care at the Ohio State University Wexner Medical Center, tells Health.

It would also extend an opportunity for people who received the one-dose J&J vaccine to “boost” with one of the mRNA (Moderna of Pfizer) vaccines if they so choose. A recent CDC study examined “real world” data from mid-March through mid-August on COVID vaccine effectiveness. The two-dose Moderna and Pfizer regimens were 93% and 88% effective, respectively, against COVID hospitalization, the study found, while the single-dose J&J vaccine had a lower level of protection, at 71%.

There’s some thought that mixing vaccines might provoke a more powerful immune response. That’s partly based on results of a small, pre-print study (not yet peer reviewed) on mix-and-match booster vaccination. Nine groups of about 50 people each participated in the study. Adults who had received one of the three COVID vaccines cleared for use in the US—Moderna, Pfizer, or J&J—were then given a booster of one of those three same vaccines.

Preliminary findings indicate that mixing and matching, regardless of the combination of vaccines and boosters, increased antibody levels, according to the New York Times. Of particular note were the results for J&J vaccine recipients: switching to a Pfizer booster resulted in a 35-fold increase in antibody levels, while those who got a Moderna booster had a 76-fold rise in antibodies. But the study has limitations, including its small size and short follow-up period, which may not capture rare side effects.

RELATED: FDA Panel Approves Moderna COVID-19 BoosterHere’s What That Means and What Happens Next

How would mixing and matching work, exactly?

Each of the COVID-19 vaccines may be given as a booster dose to eligible adults who’ve completed a different COVID vaccine. The FDA lays out a couple of scenarios.

Let’s say you had J&J. If you’re 18 or older, you could go with the J&J booster, or you could get a shot of Moderna (which, for booster purposes, is a half-dose) or a shot of Pfizer. In each case, you’ll have to wait at least two months after getting the primary J&J shot.

If you got Moderna or Pfizer and you fall into one of the categories of people authorized to get a booster, you have a choice too. You can get the same brand, you can switch to the other mRNA option, or you get J&J. Regardless of which one you choose, you’ll have to wait at least six months after you’ve completed the two-dose primary vaccine regimen.

RELATED: FDA Authorizes Pfizer Booster ShotsHere’s Who Can Get One

Are boosters already approved for each of the COVID vaccines?

Pfizer’s booster, previously cleared for use by the FDA, earned the CDC’s stamp of approval in late September. And it could be a matter of hours or days before the CDC recommends boosters for Moderna and J&J, after the FDA decided to expand use of booster doses.

The amended emergency use authorizations, announced by FDA on October 20, allow for a single booster dose in eligible adults.

Specifically, the FDA determined that a J&J booster dose may be given to adults aged 18 and older at least two months after getting the single-dose vaccine. And certain Moderna recipients (those aged 65 and older and adults 18 to 64 who are at high-risk of severe COVID or live or work in risky settings) may be eligible for a Moderna booster at least six months after the two-dose primary vaccination.

The Pfizer booster is recommended for older Americans and certain older adults with underlying conditions at least six months after completing the two-dose vaccine. Other at-risk adults and people who work in high-risk jobs where they might be exposed to COVID may also get vaccinated.

RELATED: Does the COVID-19 Boost Shot Have Side Effects? Here’s What Experts Say

Which booster should you choose?

Paul Goepfert, MD, director of the Alabama Vaccine Research Clinic at the University of Alabama at Birmingham, suspects that switching from one vaccine to another will be safe. But based on the data he’s seen, “there’s really no big advantage to mix-and-matching,” he says.

Whichever booster you get, rest assured that vaccination is highly protective against severe disease and hospitalization.

“I think these vaccines are so fantastically good that you that you can do whatever you want, and it’s going to work,” says Dr. Goepfert.

The information in this story is accurate as of press time. However, as the situation surrounding COVID-19 continues to evolve, it’s possible that some data have changed since publication. While Health is trying to keep our stories as up-to-date as possible, we also encourage readers to stay informed on news and recommendations for their own communities by using the CDCWHO, and their local public health department as resources.

To get more inspiring stories delivered to your inbox, sign up for the Healthy Living newsletter

Internet Explorer Channel Network
Asia's Tech News Daily
News Related

OTHER NEWS

Grandmother of Arthur Labinjo-Hughes in tears as balloons released in memory of murdered boy, 6, as dad & stepmum caged

ARTHUR Labinjo-Hughes' grief-stricken grandmother wept as dozens of balloons were released in memory of the tragic youngster today. Wearing a top bearing a picture of her six-year-old grandson, Madeleine Halcrow ... Read more »

Tom Holland Says He'll Play Fred Astaire in an Upcoming Film

© Getty Tom Holland Tom Holland is taking on the role of Fred Astaire. While promoting Spider-Man: No Way Home in London, the actor told the Associated Press that he’ll ... Read more »

Verstappen über dem Limit? - Rennanalyse GP Saudi-Arabien 2021

© Motorsport Images Max Verstappen – Red Bull – GP Saudi-Arabien 2021 – Jeddah – Rennen Max Verstappen kennt keine Gnade. Trotzdem verlor er das Rennen in Jeddah, weil Mercedes ... Read more »

Saquon Barkley has become face of Dave Gettleman's Giants failures

MIAMI GARDENS, Fla. — This, of course, is not all Saquon Barkley’s fault. Dolphins 20, Giants 9 on Sunday at Hard Rock Stadium wasn’t all the fault of the Giants’ ... Read more »

What Putin's India visit means for world politics

© Getty Images Russian President Vladimir Putin and Indian PM Modi have met more than a dozen times Visits by Russian presidents to India always invoke a sense of nostalgia. ... Read more »

Reports: Perdue to take on Kemp in Georgia GOP governor race

© Provided by Associated Press FILE – Georgia Gov. Brian Kemp speaks during a news conference at Lockheed Martin on Aug. 26, 2021, in Marietta, Ga. Stacey Abrams, the Georgia ... Read more »

Centre warns employees of action if their transfer requests forwarded from ministers, MPs

The Centre has warned assistant section officers under the Central Secretariat Service (CSS) cadre of disciplinary action in case transfer requests are forwarded from ministers and Members of Parliament. In ... Read more »

Omicron variant has squandered UK's progress in pandemic, top scientist warns

(Getty Images) The discovery of the omicron Covid variant has shown the world is far from the end of the pandemic and is in fact “closer to the start”, one ... Read more »

RBI weighs priority sector loans for electric vehicles

The Reserve Bank of India is considering a proposal from the Niti Aayog to categorise loans to purchase electric vehicles under the priority sector lending (PSL) segment. If the proposal ... Read more »

RBI likely to hold repo rate, keep stance unchanged

The Reserve Bank of India (RBI) will likely keep its key interest rate and monetary stance unchanged when it announces the policy on Wednesday, according to an ET poll of ... Read more »

IBC Lessons: A bird in hand is worth two in the bush

Mumbai: The plan by lenders State Bank of India and Union Bank of India to sell loans given to KSK Mahanadi Power is an example of the extent to which ... Read more »

Joining the war on COVID

A person wearing a mask. PAUL ELLIS/AFP via Getty Images I am sick of the pandemic. You are sick of the pandemic. We are all very, very sick of the ... Read more »

Medford, Oregon, plane crash leaves ‘at least 1 dead after 9-passenger plane' goes down

ONE person is reportedly dead after a plane crashed in Medford, Oregon. The nine-passenger propeller plane reportedly went down in a Chevrolet dealership on Sunday evening. Scene of the plane ... Read more »

Passports to be removed from illegal drug users in crime crackdown, Boris Johnson says

Passports to be removed from illegal drug users in crime crackdown, Boris Johnson says Boris Johnson is set to launch a ten-year plan to combat drug-related crime which will involve ... Read more »

Mind-bending optical challenges players to spot nine faces hiding in plain sight – can YOU spot them all?

ARE you up for a mind-boggling challenge? Check out this optical illusion which is hiding nine other faces in a baffling snap. If you have the patience, see how long ... Read more »

FA CUP ROUND-UP: Giant killers Yeovil punch-up again at Stevenage

© Provided by Daily Mail MailOnline logo Yeovil have made a habit of knocking EFL sides out of the FA Cup — and the National League side did it again, beating ... Read more »

Solomon Islands prime minister faces no-confidence vote after riots

© Reuters/STRINGER FILE PHOTO: FILE PHOTO: Protests turn violent in Solomon Islands By Kirsty Needham SYDNEY (Reuters) – Solomon Islands Prime Minister Manasseh Sogavare faces a motion of no confidence ... Read more »

Covid news live: Omicron found in one-third of US states, Germany plans vaccine mandates for some health jobs

LIVE – Updated at 01:30 © Photograph: Robyn Beck/AFP/Getty Images Shoppers wear protective face masks at an outdoor shopping mall in Glendale, California, on 1 December as one-third of US ... Read more »

Oil gains more than $1/bbl after Saudi price hike

By Florence Tan © Reuters/Richard Carson FILE PHOTO: A maze of crude oil pipes and valves is pictured during a tour by the Department of Energy at the Strategic Petroleum ... Read more »

Goethe-Institut launches digital magazine

© Provided by The Financial Express An art exhibition and an interactive pop-up installation were on display for the public to explore lockdown lessons through artworks and visual material produced ... Read more »

5-member TMC delegation to visit Nagaland today after civilian killings

© Provided by Hindustan Times Indian army soldiers ride past the main town in a convoy in Kohima, capital of northeastern Nagaland state, India, Sunday. (AP) A five-member delegation of ... Read more »

Omnicron scare: RTPCR testing facilities at IGI airport reviewed for passengers from at-risk countries

© Provided by Zee News New Delhi: Union Health Minister Mansukh Mandaviya reviewed RTPCR testing facilities for passengers coming from “at-risk” countries at Indira Gandhi International Airport on Sunday.  Following ... Read more »

Biden's silence on China's drug-pushing and other commentary

President Joe Biden has not recognized China‘s grand contribution to America’s deadly opioid epidemic. Al Drago/CNP/startraksphoto.com From the right: Silence on China’s Drug-Pushing “In the United States, a person dies ... Read more »

Tom Thibodeau warns ‘more changes coming' if Knicks' losing persists

Knicks coach Tom Thibodeau is not ready to make a Kemba Walker reversal, but said he won’t hesitate to make more changes if the losing continues. Among other factors, Thibodeau ... Read more »

Melanie Sykes says she's 'relieved' to be on the autistic spectrum

© Provided by Daily Mail MailOnline logo Melanie Sykes claims she felt “relief” after discovering she falls on the autistic spectrum at the late age of 51.  The TV presenter, ... Read more »

Eyes on David Warner, but Australia's biggest challenge will be when he's gone

© Getty Images Few openers in the history of the game have been able to play like David Warner © Getty Images Chris Rogers is frustrated that his memory of ... Read more »

India's Omicron tally rises to 21 with 17 more testing positive for COVID variant

© Provided by Zee News Jaipur/Mumbai/New Delhi: India reported 17 more cases of the Omicron variant of COVID-19 on Sunday – nine persons in Rajasthan capital Jaipur, seven in Maharashtra’s ... Read more »

Rain lashes several parts of Delhi-NCR, more likely in next few hours

© Provided by Zee News New Delhi: Rain lashed several parts of Delhi and its adjoining areas on Monday (December 6, 2021) morning with the India Meteorological Department (IMD) predicting ... Read more »

Oil's not well with domestic production

© Provided by The Financial Express To reduce vulnerability to high and volatile global prices, determined efforts must be made to increase the levels of relative self-sufficiency by stepping up ... Read more »

Colonel Gill who served in all 3 services passes away

© Provided by The Indian Express Colonel Prithipal Singh Gill, who had the unique distinction of having served in all three services – Army, Navy and Air Force – passed ... Read more »

Research major ties up with BITS, Woxsen

© Provided by The Financial Express “The aim is to foster industry-academia collaboration and nurture talent in emerging technologies through real-world research, while helping Course5 Intelligence to continue to provide ... Read more »

Lewis Hamilton wins crazy Saudi Grand Prix to draw level with Max Verstappen

© Provided by Zee News Lewis Hamilton won a crazy, twice-halted Saudi Arabian Grand Prix for Mercedes on Sunday (December 5) to go level on points with Red Bull rival ... Read more »

India & Russia to hold first 2+2 ministerial dialogue in Delhi. What's on agenda

© Provided by Hindustan Times Russian Foreign Affairs Minister Sergey Lavrov arrives at Delhi airport. He will take part in the 2+2 Ministerial Dialogue between India and Russia. (ANI) Russian ... Read more »

Australia job ads jump 7.4% in November -ANZ

© Reuters/Steven Saphore FILE PHOTO: A sales assistant is seen seen through the window of a retail store displaying a job vacancy sign in central Sydney, Australia SYDNEY (Reuters) – ... Read more »

Antipodeans battle to stem Omicron slide; cryptos lick weekend wounds

© Reuters/Kacper Pempel FILE PHOTO: A picture illustration of U.S. dollar Swiss Franc British pound and Euro bank notes By Tom Westbrook SYDNEY (Reuters) – Riskier currencies fought for a ... Read more »

Moonstar88 keeps us hopeful with ‘Tuloy Na Tuloy Pa Rin Ang Pasko' rendition

Moonstar88 presents a fresh, inspired take of legendary APO Hiking Society’s “Tuloy Na Tuloy Pa Rin Ang Pasko.” © Provided by LionhearTV The Moonstar88 rendition is a slow-paced version of ... Read more »

Strictly's AJ Odudu And John Whaite Both Struck By Dance Disasters Thanks To Tricky Lifts

Strictly Come Dancing favourites AJ Odudu and John Whaite both found themselves slipping down this week’s leaderboard after disaster struck their respective Salsa routines. Both stars came unstuck with lifts ... Read more »

Gaming laptops are about to get more expensive, Razer's CEO warns

© Provided by Dot Esports Want a good gaming laptop? Then you might want to get one now before prices rise, according to a warning from Razer. The peripheral and ... Read more »

Storm Barra hits tomorrow with four inches of snow and 70mph gales at start of five-day deep freeze

A STORM is set to batter Britain this week with weather warnings issued across much of the country. The 500-mile wide storm Barras is expected to arrive in the UK ... Read more »

Masks rules ‘to stay until New Year' amid Omicron crisis as PM ‘desperate not to ruin Christmas' with tougher measures

FACE mask rules could be in place “until the New Year” as Boris Johnson desperately tries not to ruin Christmas with tougher measures. It comes nearly a week after emergency ... Read more »
On free-english-test.com you will find lots of free English exam practice materials to help you improve your English skills: grammar, listening, reading, writing, ielts, toeic