Covid Shot From China's Clover Found 79% Effective Against Delta

(Bloomberg) — A vaccine developed by Sichuan Clover Biopharmaceuticals Inc. was found to prevent 79% of Covid-19 cases caused by the delta strain in late-stage trials, making it the first Chinese shot to offer clear efficacy data against the variant causing resurgent virus waves around the world.

Most Read from Bloomberg

  • Istanbul Turns Taps on Old Fountains, Joining Global Push for Free Drinks
  • The Global Housing Market Is Broken, and It’s Dividing Entire Countries
  • In Paris, the Wrapped Arc de Triomphe Is a Polarizing Package
  • How the Child Care Crisis Became a Global Economic Fiasco
  • Merkel’s Legacy Comes to Life on Berlin’s ‘Arab Street’

The Clover candidate deploys protein on the coronavirus to stimulate immunity against Covid, an approach also used by the shot developed by Novavax Inc. It is 100% effective against severe Covid caused by any variants detected in the trial, including delta, gamma and mu, which first emerged from India, Brazil and Colombia respectively.

The vaccine prevented 67% of Covid of any severity caused by any strain, the company based in the western Chinese city of Chengdu said in a press release on Wednesday. 

The efficacy data was based on a total of 207 cases of symptomatic Covid two weeks after clinical trial participants received the second dose of either the Clover shot or a placebo. Genetic sequencing was conducted on 146 of the cases, with the delta, mu and gamma variants accounting for nearly three-quarters of them. The trial enrolled more than 30,000 adults and elderly across the Philippines, Brazil, Columbia, South Africa and Belgium, according to the company’s statement.

The shot, given in two doses at a three-week interval, is the first Chinese inoculation to demonstrate definitive evidence as to its potency against predominant variants around the world.

Inactivated vaccines made by Beijing-based Sinovac Biotech Ltd. and state-owned Sinopharm are among the most used in China and other parts of the world, and have efficacy rates ranging from around 50% to 80% in preventing symptomatic Covid. That’s below the 90% rates seen in Phase III trials of the mRNA shots developed by Pfizer Inc/BioNTech SE and Moderna Inc.

Sinovac and Sinopharm have also provided little conclusive data on the effectiveness of their shots against delta, which is more infectious than the virus’ original strain and appears to have dimmed the protection of existing vaccines.

Chinese vaccine maker Chongqing Zhifei Biological Products Co. said in August that its Covid vaccine — which is similar to the Clover candidate but requires three doses — was found to be almost 78% effective against delta and 92.93% effective against the alpha variant, though it didn’t specify whether the figures were for serious illness or all symptomatic infections.  

Clover’s shot was developed with $328 million in funding from the Coalition for Epidemic Preparedness Innovations, which has also backed the development of the AstraZeneca Plc and Moderna Covid vaccines. Clover signed an agreement with vaccine alliance Gavi to supply up to 414 million doses to Covax, a program backed by the World Health Organization to ensure access to shots for the world’s poorest nations.

The company will apply for approval of the vaccine with regulators in China, the European Union and the World Health Organization in the fourth quarter of this year, and expects to roll out the shot by the end of 2021, Clover said in the statement.

Most Read from Bloomberg Businessweek

  • In Amazon’s Flagship Fulfillment Center, the Machines Run the Show
  • Microsoft and an Army of Tiny Telecoms Are Part of a Plan to Wire Rural America
  • Evergrande Debt Crisis Is Financial Stress Test No One Wanted
  • ‘Just Get Me a Box’: Inside the Brutal Realities of Supply Chain Hell
  • Germany’s Industrial Giants Confront Their Mortality on Election Eve

©2021 Bloomberg L.P.

Internet Explorer Channel Network
News Related

OTHER NEWS

Purdue Shuts Down No. 2 Iowa in Upset at Kinnick

© Provided by Sports Illustrated The win at Kinnick adds another historic victory for the Boilermakers, who handed the Hawkeyes their first loss of 2021. View the original article to ... Read more »

Norwich City vs Brighton: Canaries, Seagulls waste chances for win

© Provided by NBC Sports Norwich City and Brighton and Hove Albion will both look back on Saturday’s 0-0 draw as a blown chance to meet their season goals head-on ... Read more »

Gamethread: Red Wings vs Canucks

© Photo by Gregory Shamus/Getty Images Vancouver Canucks Team Detroit Red Wings 2-0-0 – 4 Points Record 0-0-1 1 Point Thatcher Demko Starting Goaltender Alex Nedeljkovic Nucks Misconduct SB Nation ... Read more »

Texas Xfinity race results, driver points

FORT WORTH, Texas – John Hunter Nemechek rallied from a pit road penalty to win Saturday’s Xfinity Series race at Texas Motor Speedway. © Provided by NBC Sports Nemechek, a ... Read more »

Bill Clinton to spend one more night in hospital with non-Covid infection

Former US President Bill Clinton will spend another night at a hospital in California being treated for an infection, his spokesman said Saturday.  © Martin BUREAU Bill Clinton, recovering from ... Read more »

Russia breaks record with over 1,000 COVID-19 deaths in 24 hours

Russia hit over 1,000 COVID-19 deaths in 24 hours on Saturday, breaking the record for the most daily deaths from the virus in the country. © Getty Images Russia breaks ... Read more »

NHL 22: How to increase your playing time in Be a Pro

After you’ve made your character in Be a Pro, you’re going to want your new hockey star to spend as much time playing on the ice as possible. The key ... Read more »

Overwatch 2 Developers Tease Changes Coming to Healers

The developers are beginning to share more information about Overwatch 2 as the game nears it unannounced 2022 release date. Recently, the sequel’s hero design and balancing team hosted a ... Read more »

Clinton expected to be out of hospital Sunday

Former President Bill Clinton was expected to be released from a Southern California hospital Sunday, a spokesperson said. © Provided by NBC News “President Clinton has continued to make excellent ... Read more »

Joe Manchin blasts 'out-of-stater' Bernie Sanders over infrastructure op-ed in West Virginia newspaper

© Provided by Business Insider Sen. Joe Manchin of West Virginia. Samuel Corum/Getty Images Manchin blasted Bernie Sanders for writing an op-ed in a W.Va. paper over the reconciliation bill. ... Read more »

A secure UK gas supply is meaningless, minister, if no one can pay their bills

At first glance, the government’s much-delayed bid to break Britain’s decades-long addiction to gas heating is well timed, as the nation braces itself for a winter energy crisis. © Provided ... Read more »

A new look at a venerable span: Historian takes deep, detailed dive into construction of the Brooklyn Bridge

After 40 years of being a fan, historian Jeffrey Richman’s labor of love is done: a beautifully illustrated new book about the 14-year construction of the Brooklyn Bridge. The former ... Read more »

Why was Red Sox-Astros ALCS Game 2 delayed? MLB pitching change rules, explained

When a baseball game is delayed, it’s usually because of inclement weather. Playing in a retractable-roof stadium like Minute Maid Park in Houston usually helps to eliminate just about any ... Read more »

Former President Clinton expects to be discharged from Orange County hospital on Sunday

Former President Clinton is expected to be released from an Orange County hospital on Sunday after spending nearly a week there because of an infection, a spokesman said. © Provided ... Read more »

Grizzlies cut ex-lottery pick Kris Dunn, two others

The Grizzlies have waived former lottery pick Kris Dunn, the team announced Saturday in a press release. Matthew Hurt and David Stockton have also been cut, as Memphis finalizes its ... Read more »

President Clinton making progress, expected to be discharged Sunday, spokesperson says

Former President Bill Clinton will remain at University of California Irvine Medical Center in Orange, California, for at least one more night, and is expected to be discharged Sunday, his ... Read more »

We ask the experts for menopause signs & symptoms every woman should know about

ONCE you hit your late 40s, every sweaty moment, muscle cramp and mood swing can have you questioning if it has started. By it, we mean the menopause. But, as ... Read more »

Red Sox Make Playoff History With Two Grand Slams in First Two Innings vs. Astros

© Provided by Sports Illustrated J.D. Martinez and Rafael Devers led Boston to a 8–0 lead after just two innings in Game 2 of the American League Championship Series at ... Read more »

Broncos open practice window for Jerry Jeudy

© Provided by NBC Sports Broncos receiver Jerry Jeudy suffered a sprained ankle in the season-opening win over the Giants. He landed on injured reserve. He’s now closer to returning. ... Read more »

Ex-Sparks star Candace Parker fires up hometown fans as Sky close in on WNBA title

For 14 years, Candance Parker heard all about the WNBA’s growth. TV audiences are soaring. NBA stars fill courtside seats. She’s even been the face of the league’s evolution, becoming ... Read more »

Sofia Vergara Is a Chic Tourist in Black Monochromatic Look and Chunky Combat Boots

© River / MEGA SofiaVergara Sofia Vergara is keeping up with Irish tradition and fun nights in a sleek monochromatic ensemble. Lately, the Colombian actress has been posting her vacation ... Read more »

Robert Durst on Ventilator With COVID Following Life Sentence for Murder: Lawyer

Robert Durst, a real estate heir sentenced to life in prison for murder on Thursday, has been placed on a ventilator with COVID-19, his attorney said on Saturday. © Pool ... Read more »

Native American Group Calls on Fox News to Fire Hosts Over ‘Racist' Comments

A Native American organization is calling on Fox News to fire hosts Jesse Watters and Rachel Campos-Duffy over a segment in which they tied Native Americans’ struggles to “government dependency” ... Read more »

Lucas Moura eager to help end Tottenham's wait for a trophy

© Provided by Daily Mail MailOnline logo Lucas Moura is ready to embrace the pressure of helping to end Tottenham’s trophy drought this season and fire Spurs back into the ... Read more »

Cam Newton reportedly receives COVID-19 vaccine as he looks to sign with NFL team

Cam Newton appears to be doing all he can to make himself signable for an NFL team. Newton has received the COVID-19 vaccine as teams have remained in contact with ... Read more »

Australia secures two new “breakthrough” Covid treatments

More than half-a-million additional doses of Covid-19 treatments have been secured for Australians, with the first 5000 expected to arrive by the end of the month. The Federal Government on ... Read more »

China surprised US officials with August missiles test: Report

China surprised U.S. officials by testing a new hypersonic missile in August that went around the globe before it made its way toward the intended target, a new report says. ... Read more »

Robert Durst is on a ventilator with COVID-19 just days after being sentenced to life in prison, lawyer says

© Myung J. Chung/Los Angeles Times via Associated Press New York real estate scion Robert Durst, 78, sits in the courtroom as he is sentenced to life in prison without ... Read more »

Official Wizard of New Zealand fired by city council after more than 2 decades

For more than two decades, the New Zealand city of Christchurch has annually paid thousands of dollars to Ian Brackenbury Channell, known as the official Wizard of New Zealand. © ... Read more »

Chris Stapleton concert rescheduled until November

© Provided by Sioux Falls(Mitchell) KSFY KSFY SIOUX FALLS, S.D. (Dakota News Now) – Country music superstar Chris Stapleton is rescheduling his Sioux Falls concert after coming down with laryngitis. ... Read more »

Deal Alert: Fly business class to Thailand for 70k miles one-way

© Provided by The Points Guy MSN has partnered with The Points Guy for our coverage of credit card products. MSN and The Points Guy may receive a commission from ... Read more »

Black Louisiana trooper who accused colleagues of murder in case of Ronald Greene says he was fired

The Louisiana state trooper who accused colleagues of murdering a man in an alleged coverup said that he was fired from his position. In June, the ex-trooper, Carl Cavalier, said ... Read more »

Maduro envoy extradicted to US from Cape Verde

An envoy for Venezuelan President Nicholas Maduro has been extradited to the U.S. on Saturday, Cape Verde national radio said. © Getty Maduro envoy extradicted to US from Cape Verde ... Read more »

NASA's Lucy mission launches, will swing past eight asteroids

© Provided by Daily Mail MailOnline logo A nearly billion dollar NASA spacecraft named Lucy officially launched on Saturday morning, in what is the beginning of a 12-year journey to ... Read more »

Tiffany & Co. to Mentor Young People on Creative Team

© Henry Leutwyler/Courtesy Click here to read the full article. PARIS – In a sign of its reinvention under new owner LVMH Moët Hennessy Louis Vuitton, Tiffany & Co. is ... Read more »

William Shatner hits back after George Takei called him a 'guinea pig' and 'unfit' following Blue Origin spaceflight

© Blue Origin Left to right: Chris Boshuizen, William Shatner, Audrey Powers, and Glen de Vries in their Blue Origin flight jumpsuits. Blue Origin William Shatner responded to George Takei’s ... Read more »

Tennessee vs. Ole Miss odds, line: 2021 college football picks, Week 7 predictions from proven computer model

Lane Kiffin returns to Neyland Stadium for the first time as an opposing head coach when the No. 13 Ole Miss Rebels (4-1) travel to take on the Tennessee Volunteers ... Read more »

“We're done”: Immigration advocates stage walk-out on Biden administration

Dozens of immigration advocates walked out, virtually, on top Biden officials Saturday in protest of the administration’s decision to continue border policies enacted during the Trump administration, according to several ... Read more »

'Voice' Coaches Are Getting A Lot of Heat From Fans After Controversial 'Battles' Elimination

The Battles on The Voice are officially underway, and fans of the NBC singing competition show already have a bone to pick with the coaches. It all began on Monday ... Read more »

See J.D. Martinez, Rafael Devers blast 2 grand slams in 2 innings against the Astros in ALCS

Things got hot quickly between the Boston Red Sox and Houston Astros in Game 2 of the ALCS on Saturday, thanks to J.D. Martinez and his stunning first-inning grand slam. ... Read more »