Mississippi State vs. Ole Miss odds, line, spread: 2023 Egg Bowl picks, prediction, bets from proven model

Oct 24, 2015; Atlanta, GA, USA; Georgia Tech Yellow Jackets helmet on the field before a game against the Florida State Seminoles at Bobby Dodd Stadium.

The Mississippi State Bulldogs will play their second game this season under interim coach Greg Knox when they host the Ole Miss Rebels in the 2023 Egg Bowl on Thanksgiving night at Davis Wade Stadium. The 60-year-old Knox took over on an interim basis last week after Zach Arnett was fired following a 4-6 start. This is the second time Knox has been interim head coach in Starkville, after his one-game stint to close out the 2017 season. Meanwhile, Ole Miss coach Lane Kiffin, who is in his fourth season in Oxford, is looking for his second 10-win season in the last three years.

Kickoff is scheduled for 7:30 p.m. ET. The Rebels are 10-point favorites in the latest Ole Miss vs. Mississippi State odds via SportsLine consensus, while the over/under for total points scored is 54. Before making any Mississippi State vs. Ole Miss picks, you need to see the college football predictions and betting advice from SportsLine’s proven computer model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, the proprietary computer model has generated a strong profit of well over $2,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed the model has seen huge returns.

Now, the model has set its sights on Ole Miss vs. Mississippi State and just locked in its picks and predictions. You can visit SportsLine now to see the model’s CFB picks. Here are several college football odds and trends for Mississippi State vs. Ole Miss:

• Mississippi State vs. Ole Miss spread: Rebels -10
• Mississippi State vs. Ole Miss over/under: 54 points
• Mississippi State vs. Ole Miss money line: Rebels -388, Bulldogs +303
• MISS: The Rebels rank fourth in the country in fewest turnovers (seven)
• MSST: LB Jett Johnson leads the conference in total tackles (99)

Why Ole Miss can cover

The Rebels have a plethora of pass-catching weapons. Ole Miss is one of just two teams in the country with three 700-yard receivers: Tre Harris (824), Jordan Watkins (734) and Dayton Wade (755). Harris, a transfer from Louisiana Tech, is the only FBS receiver this season with both a 200-yard game and a four-touchdown performance. Ole Miss’ receivers have a plus matchup against a Mississippi State defense that ranks 115th in the country in pass efficiency defense (148.80).

In addition, Ole Miss faces a Bulldogs offense that has struggled all season. Mississippi State ranks 103rd in the nation in total offense (330.9 yards per game) and 92nd in scoring offense (23.2 points per game). See which team to pick here.

Why Mississippi State can cover

Senior linebacker Nathaniel Watson is a relentless playmaker on defense. The 6-foot-2, 245-pound senior ranks second in the conference in tackles (116), one year after finishing second in the SEC last season. In a 41-20 victory over Southern Miss last week, Watson made a career-high 21 tackles, the most by an SEC defender since 2017. He also registered a forced fumble and his 10th sack of the season.

In addition, Watson and the rest of the Mississippi State defense face an Ole Miss offense that has struggled with penetration this season. The Rebels rank 114th in the country in tackles for loss allowed per game (7.18). They also are 80th in sacks allowed per game (2.27). See which team to pick here.

How to make Ole Miss vs. Mississippi State picks

SportsLine’s model is leaning Under the point total, predicting a combined 54 points. The model also says one side of the spread hits over 60% of the time. You can see the model’s CFB picks at SportsLine.

So who wins Mississippi State vs. Ole Miss, and which side of the spread hits more than 60% of the time? Visit SportsLine now to see which side of the spread you need to jump on, all from the model that has notched a profit of well over $2,000 on its top-rated college football spread picks, and find out.