Astrazeneca feels force of cancer drug hopes

© Provided by This Is Money MailOnline logo

Pharma giant Astrazeneca was a top riser on the FTSE 100 yesterday after a strong week that saw it reporting positive clinical data for two cancer drugs. 

Data released yesterday from a clinical trial for its lynparza tablets showed a ‘statistically significant and clinically meaningful improvement’ in the survival of men suffering from prostate cancer, it said. 

Prostate cancer is the most common cancer in men, with around one in eight in the UK diagnosed with it during their lifetime. It claims over 11,500 lives a year. 

© Provided by This Is Money (

‘Today, men with prostate cancer have limited options and sadly often the disease progresses after initial treatment with current standards of care,’ said Susan Galbraith, Astra’s vice-president of oncology research and development. 

‘These exciting results demonstrate the potential for lynparza… to become a new first-line option for patients… and reach a broad population of patients living with this aggressive disease. We look forward to discussing the results with global health authorities as soon as possible.’ 

Lynparza is already approved in multiple countries including the US and Japan to treat breast, ovarian and pancreatic cancers. 

The clinical trial success could be highly lucrative, according to analysts at Jefferies, who said that the 30,000 to 50,000 patients suffering from the cancer in the US alone presented a ‘significant commercial opportunity’ of £2.2billion to £3.7billion in sales. 

Globally, the drug could be worth up to £7.3billion, they said. 

Analysts at Shore Capital said: ‘This ‘pipeline in a pill’ model has been implemented successfully for numerous oncology assets in Astrazeneca’s portfolio and we see the potential for other assets in development to achieve equally impressive results.’ 

Since taking over in 2012 chief executive Pascal Soriot has focused on launching blockbuster oncology drugs, boosting the share price, which rose 2 per cent, or 177p, to 8845p yesterday. It is the second win in a week for Soriot and the drugs giant. 

© Provided by This Is Money 190093363
© Provided by This Is Money

On Monday, results from a phase III trial showed its cancer drug enhertu reduced the risk of disease progression and death by 72 per cent in patients with metastatic breast cancer (MBC), also known as stage IV breast cancer, when the disease spreads to another part of the body. 

Galbraith said the enhertu results represented a ‘potential paradigm shift in the treatment of HER2-positive metastatic breast cancer and illustrate the potential to transform more patient lives in earlier treatment settings’.

It means that the drug is better at keeping patients alive without their tumours worsening than a drug developed by Roche, Astra’s Swiss rival. 

MBC has a low survival rate, averaging at around three years.

Internet Explorer Channel Network
News Related

OTHER NEWS

Valorant: How To Play With a Controller Complete Guide

Valorant is one of the fastest-growing FPS shooters on PC that focuses on using a mouse and keyboard, but can you use a controller to play the game? © GiveMeSport ... Read more »

French fishermen threaten Channel blockade as Macron snubbed by EU countries

Fishermen gut freshly caught fish aboard fishing boat ‘About Time’ while trawling in the English Channel from the Port of Newhaven, East Sussex, U.K – Jason Alden /Bloomberg France’s failure ... Read more »

Robert Webb Labels Strictly Come Dancing ‘Brutal' And ‘Weird': ‘I Was Almost Weeping As It Is So Intense'

Robert Webb labelled Strictly Come Dancing “brutal” and “weird” just a week before he quit the BBC dance show due to health concerns. On Wednesday, the Peep Show star announced ... Read more »

Adam Peaty's girlfriend reacts to Strictly star's ‘almost kiss' with dance partner Katya Jones

The girlfriend of Strictly Come Dancing star Adam Peaty has shared her reaction after he and dance partner Katya Jones supposedly “almost kissed” after their performance last night (Saturday 16 ... Read more »

Usman Khawaja scores big Sheffield Shield century for Queensland against South Australia

A ton of defiance from Usman Khawaja has inspired a remarkable Queensland revival in their Sheffield Shield clash against South Australia, just as Australia is looking for an opener for ... Read more »

Why I won't use iPhone 13's MagSafe wallet, even though it's better than ever

There’s nothing more frustrating than misplacing an item; whether it’s the TV remote, your house keys, or your wallet. Spending time searching for the item, or worse, forking out to ... Read more »

We could get a Nothing phone from ex-OnePlus co-founder in 2022

When Carl Pei left the OnePlus company he co-founded, the talk was that a phone would eventually emerge out of his new project – and that now seems likelier than ... Read more »

Nationals seek further climate plan detail

The Nationals have asked for more details on a plan to achieve net zero emissions by 2050, following a passionate four-hour meeting in Canberra. © Mick Tsikas/AAP PHOTOS Barnaby Joyce ... Read more »

China's tech regulator says scrutiny of internet industry to deepen as targeted six-month campaign continues

China’s industry regulator plans to deepen scrutiny of the internet industry as it moves into the second half of a six-month campaign launched in July, the agency’s minister told Chinese ... Read more »

What you can do in NSW from tomorrow now we've hit 80 per cent

New South Wales has ticked over the long-awaited 80 per cent COVID-19 vaccine target, unlocking a new set of freedoms from tomorrow. These include changes to how many people you ... Read more »

Female directors wait longer than men for their big break, report reveals

Television documentary teams in Britain today are full of ambitious and capable women but most of them have to wait much longer than their male colleagues to become directors and ... Read more »

Eddie Redmayne 'loved' being at home during lockdown

Eddie Redmayne learned to grow vegetables during lockdown. © Bang Showbiz Eddie Redmayne The ‘Fantastic Beasts and Where To Find Them’ actor “loved” spending more time at home with his ... Read more »

Mum, 25, with terminal skin cancer reveals heartbreaking discovery

© Provided by Daily Mail MailOnline logo A terminally ill mother who went home to Ireland after she was given months to live says she has been ‘robbed’ by its ... Read more »

Solar panels, hydrogen and wireless charging – Kia has big plans for its EV future

Kia’s electric car portfolio is already pretty strong, with the Soul EV, the eNiro and the new EV6 now available, but the South Korean firm isn’t resting on its laurels. ... Read more »

Can sugarcane shoes help you recover from a marathon? We put them to the test

There’s been a recent surge in popularity of eco-friendly running shoes, with brands including Reebok, Salomon and Brooks all launching shoes made from sustainable and recycled materials. Meanwhile Allbirds – ... Read more »

Nationals fail to land on climate position during marathon meeting as Barnaby Joyce warns party will not be bullied

© Provided by ABC NEWS Barnaby Joyce said the meeting was an opportunity for Nationals colleagues to air the concerns of people in their electorates.  (ABC News: Ian Cutmore) The ... Read more »

Two charged over Sunshine Coast stabbing

A man will face court tomorrow following an assault that left three people with multiple stab wounds on Queensland’s Sunshine Coast. © Tracey Nearmy/AAP PHOTOS Queensland police have charged two ... Read more »

Sydneysiders scramble to book flights before November 1 opening date

© Provided by Daily Mail MailOnline logo Thousands of holiday-hungry Australians raced to book an overseas holiday after NSW announced it would reopen its international border on November 1.   Vaccinated ... Read more »

French ambassador returns to Australia after submarine snub

The French ambassador to Australia has arrived in Sydney, returning weeks after being called back to Paris. Jean-Pierre Thebault landed on Sunday afternoon saying he was “happy to be back” ... Read more »

Shirley Ballas books doctor's appointment after concerned Strictly Come Dancing viewers spot ‘lumps' in her armpit

Shirley Ballas has informed fans she has booked a doctor’s appointment after several Strictly Come Dancing viewers raised concern over “lumps” they’d noticed in her armpit. The head judge, 61, ... Read more »

Yeah Adam Peaty's Girlfriend Noticed Him ‘Almost Kissing' His Strictly Partner Katya Jones After Their Argentine Tango Too

Adam Peaty impressed with his Argentine Tango on Saturday night’s Strictly Come Dancing, but it was the very end of the dance that had everyone talking. As the Olympic swimmer ... Read more »

Matt Hancock loses UN job just four days after his appointment

Matt Hancock pictured in London earlier this year – Mega Matt Hancock has lost his new job at the United Nations just four days after being appointed, following outrage from ... Read more »

New partners and babies on the way. The Married at First Sight cast: Where are they now?

Married At First Sight had us glued to our TV screens for the better part of 2021. © Getty Images New partners and babies on the way. The Married at ... Read more »

Black Friday mattress deals 2021: early sales and our predictions

Black Friday is an excellent time of year to save money on a mattress. Big price drops, extra free gifts, and more offers to choose between than usual make November ... Read more »

Berejiklian ICAC hearings set to begin weeks after shock resignation

Two weeks since her sudden resignation as premier and a year after she first revealed her years-long secret relationship with a disgraced former MP, a corruption inquiry is this week ... Read more »

Countdown on for S. Korea‘s self-developed satellite launcher Nuri

A model of South Korea’s homegrown space rocket Nuri is connected to a launch pad at the Naro Space Center in Goheung. (KARI)South Korea will test its first domestically-developed satellite ... Read more »

Life as a 'foreign agent': Inside Russia's crackdown on free speech

Instead of overt brutality, this latest campaign is being waged quietly with a vague legal tool: a law regulating the activities of so-called foreign agents. Read more »

Joyce expects colleagues to reject deeper cuts to greenhouse gas emissions by 2030

Nationals leader Barnaby Joyce expects his colleagues to reject the idea of making deeper cuts to greenhouse gas emissions by 2030 despite support within the government for stronger action on ... Read more »

Shane Warne vows to make Melbourne 'great again'

© Provided by Daily Mail MailOnline logo Australian cricketing icon Shane Warne has vowed to make Melbourne ‘great again’ after months of harsh lockdowns. Taking to Twitter on Saturday, the ... Read more »

Australia to allows flights from New Zealand's South Island

Quarantine-free flights between Australia and New Zealand‘s South Island are set to resume from Tuesday. Meanwhile, Australians remain unable to freely travel to and from New Zealand‘s North Island. Australia’s ... Read more »

Maggie Gyllenhaal attends the Mill Valley Film Festival

© Provided by Daily Mail MailOnline logo Maggie Gyllenhaal and Dakota Johnson were spotted posing for a few photos while attending a screening of The Lost Daughter at the Mill ... Read more »

Casualty wasn't on air this weekend, explained

Photo credit: BBC Casualty spoilers follow. Casualty did not air its latest episode as planned this weekend, as the BBC pulled Saturday's new episode from the schedules due to tragic ... Read more »

Daniel Craig appears as surprise guest alongside Rami Malek on SNL

Daniel Craig appears as surprise guest alongside Rami Malek on SNL Daniel Craig made a surprise appearance on Saturday Night Live tonight (October 17). Craig appeared alongside his No Time ... Read more »

Billy Connolly: ‘It might be lovely on the other side'

A fostered-off schoolboy going nowhere fast, turned apprentice welder on the Clyde. A welder turned regionally popular musician. A musician turned nationally popular comic. A comic turned Hollywood actor and ... Read more »

How to watch T20 World Cup 2021: live stream online from anywhere

India vs Pakistan, Australia vs South Africa, and a repeat of the 2016 final are just a snapshot of what we’ve got to look forward to before we even get ... Read more »

S. Korea's car production drops in Q3 on global chip shortage

An assembly line at GM Korea’s factory Bupyeong, Incheon. (GM Korea)South Korea’s car production in the third quarter this year dropped, marking the lowest level since the 2008 global financial ... Read more »

Amazon puts its own “brands” first above better-rated products

It took Robert Gomez about five months to get his Kaffe coffee grinder to the big leagues in e-commerce: among the first three search results for “coffee grinder” on Amazon.com. ... Read more »

Hyundai Motor aims to produce its own semiconductors

Hyundai Motor and Kia Corp. headquarters in Seoul / Courtesy of Hyundai Motor Group By Kim Hyun-bin Hyundai Motor Group is taking steps to advance beyond its traditional strength of ... Read more »

AhnLab's coding class for employees

An AhnLab employee and his son learn coding via a metaverse platform at the cybersecurity company’s headquarters in Pangyo, Gyeonggi Province, Saturday. AhnLab held the event for its employees and ... Read more »

SAS Australia 'was The Sam Burgess Show from day one' sources claim

© Provided by Daily Mail MailOnline logo A source exclusively revealed to Daily Mail Australia last week that one recruit on this year’s SAS Australia was given preferential treatment all ... Read more »